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Comment & Response
February 20, 2018

Organ Dysfunction After Surgery in Patients Treated With Individualized or Standard Blood Pressure Management

Author Affiliations
  • 1Department of Anesthesiology, University of Virginia School of Medicine, Charlottesville
JAMA. 2018;319(7):720. doi:10.1001/jama.2017.20923

To the Editor A randomized clinical trial comparing a standard blood pressure management regimen vs individualized therapy in patients undergoing major surgery suggested that individualized goals could reduce postoperative organ dysfunction.1 Unfortunately, the conclusions of the Intraoperative Norepinephrine to Control Arterial Pressure (INPRESS) study are not fully supported by the data.