In Reply Dr Karamchandani and colleagues suggest that exposing patients in the standard treatment group to a blood pressure threshold level lower than what is generally accepted may have predisposed patients to organ dysfunction. However, although there is accumulating evidence that intraoperative blood pressure is associated with outcomes, the goals for blood pressure are not well supported by robust evidence and there are few data to support any specific threshold.
Futier E, Pereira B, Jaber S. Organ Dysfunction After Surgery in Patients Treated With Individualized or Standard Blood Pressure Management—Reply. JAMA. 2018;319(7):721–722. doi:10.1001/jama.2017.20956
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