Since hormonal contraception became available in 1960—in the form of a combined estrogen-progestin pill—researchers have evaluated its risks and benefits. Though widely recognized as a breakthrough in medicine and the first effective long-term, reversible method of birth control, hormonal contraception, which is used by an estimated 140 million women worldwide, has never been free of adverse effects.
Peachman RR. Weighing the Risks and Benefits of Hormonal Contraception. JAMA. 2018;319(11):1083–1084. doi:10.1001/jama.2018.0448
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