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JAMA Clinical Challenge
March 20, 2018

Peristomal Nodule in a Patient With Ovarian Cancer

Author Affiliations
  • 1Department of Dermatology, Yale School of Medicine, New Haven, Connecticut
  • 2Yale School of Medicine, New Haven, Connecticut
JAMA. 2018;319(11):1158-1159. doi:10.1001/jama.2018.0770

A 56-year-old woman with a history of ovarian cancer and surgical colostomy presented with a nontender nodule adjacent to her stoma. She was diagnosed 6 years ago with recurrent poorly differentiated serous ovarian carcinoma and underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy, with multiple regimens of chemotherapy, most recently with ixabepilone and bevacizumab. Complications included a large bowel obstruction, for which she underwent a transverse loop colostomy 3 years ago.