Seventeen years have passed since the US National Academy of Medicine (NAM) (then the Institute of Medicine) published Crossing the Quality Chasm, a major effort to outline an approach to improving health care quality.1 One of the recommendations for improving care envisioned the broader use of evidenced-based clinical practice guidelines (CPGs) as a pathway toward standardization and improved outcomes. The success of this strategy would depend on the supply of trustworthy CPGs and the demand by both clinicians and organized health systems to deploy those CPGs. Quality metrics derived from CPGs were expected to be guideposts for health systems to gauge performance.