Individuals with frontotemporal dementia (FTD) experience progressive behavioral changes accompanied by cognitive and functional decline. However, this process is not always one of inexorable decline, as occasionally loss in one area of function can lead to enhancement in others. This phenomenon, known as paradoxical functional facilitation, occurs when suppression or loss of activity in one part of the brain leads to a release of activity in another.1 Over the years, we have cared for many patients with FTD who experience a sudden onset increase in artistic creativity. Here we describe 2 patients who exemplify the phenomenon.
Erkkinen MG, Zúñiga RG, Pardo CC, Miller BL, Miller ZA. Artistic Renaissance in Frontotemporal Dementia. JAMA. 2018;319(13):1304–1306. doi:10.1001/jama.2017.19501
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