A young adult was diagnosed with community-acquired pneumonia after presenting with productive cough and fevers. Despite treatment, she remained febrile and was hospitalized due to progressive hypoxemia, a pleural effusion, and bilateral pulmonary emboli. Laboratory tests revealed new-onset anemia, thrombocytosis, and red blood cell (RBC) agglutination (Table). Direct antiglobulin test (DAT) results were positive. Subsequent testing revealed an elevated Mycoplasma pneumoniae titer.
Stein B, DeCredico N, Hillman L. Evaluation of the Direct Antiglobulin Test (DAT) in the Setting of Mycoplasma pneumoniae Infection. JAMA. 2018;319(13):1377–1378. doi:10.1001/jama.2018.1969
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