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May 1, 2018

Nitrofurantoin vs Fosfomycin: Rendering a Verdict in a Trial of Acute Uncomplicated Cystitis

Author Affiliations
  • 1Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut
JAMA. 2018;319(17):1771-1772. doi:10.1001/jama.2018.4654

Urinary tract infections (UTIs) are common and contribute a significant burden to population health. In the United States, UTIs account for approximately 10 million ambulatory visits and an estimated $2 billion in total costs each year.1,2 Compared with men, women incur a greater burden of disease, with more than half of women experiencing at least 1 UTI during their lifetime.3 Among women aged 18 to 70 years, acute uncomplicated UTI results in nearly 4 days of genitourinary symptoms and 3 days of restricted activity per episode.4