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Clinical Trials Update
April 24, 2018

Vegetarian and Mediterranean Diets Effective for Weight Loss

JAMA. 2018;319(16):1649. doi:10.1001/jama.2018.4738

A lacto-ovo vegetarian diet (VD) and the Mediterranean diet (MD) were equally effective in reducing body weight, body mass index (BMI), and fat mass, according to a study published in Circulation. The vegetarian diet, however, was more effective in reducing low-density lipoprotein (LDL) cholesterol levels, while the MD significantly reduced triglyceride levels.

The 118 overweight participants (average age, 51.1 years), who had low to moderate cardiovascular risk were randomly assigned to a low-calorie VD or to a low-calorie MD for 3 months, after which they crossed over to the other diet. The participation rate at the end of the study was 84.7%.