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Comment & Response
May 8, 2018

Antibiotic Prophylaxis for Removal of Lower Leg Orthopedic Implants—Reply

Author Affiliations
  • 1Trauma Unit, Academic Medical Center Amsterdam, Amsterdam, the Netherlands
JAMA. 2018;319(18):1936-1937. doi:10.1001/jama.2018.2852

In Reply We think that the 14% SSI rate found in our study is in concordance with the most recent literature on this subject. In a contemporary study, the SSI rates following implant removal were up to 12.2%.1 Furthermore, these studies were either retrospective or did not involve an intervention. Retrospective studies have often shown lower rates of SSI due to underreporting, which may explain the slightly higher SSI rate in our study.