In Reply Dr Chang and colleagues correctly note that inclusion of underrepresented populations in research is key to addressing health disparities and advancing health equity. In addition to the underrepresented populations mentioned in our Viewpoint (children, older adults, pregnant and lactating women, individuals with physical and intellectual disabilities), the writers correctly add LGBT individuals. We agree that more studies are needed on how educational level, family dynamics, and other social and environmental factors affect not only the health of underrepresented populations but also their participation and retention in clinical research. We also concur that enhanced training and mentoring of researchers from underrepresented populations is an important step in making inclusion a routine approach and in helping to eliminate health disparities.
Spong CY, Bianchi DW. Research on Underrepresented Populations—Reply. JAMA. 2018;319(19):2045. doi:10.1001/jama.2018.4098
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