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May 22/29, 2018

Prenatal vs Infant Vitamin D Supplementation and the Risk of Wheezing in Childhood

Author Affiliations
  • 1Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison
JAMA. 2018;319(20):2081-2082. doi:10.1001/jama.2018.5726

The benefits of vitamin D supplementation are an area of intense scientific and clinical interest. Although the association of vitamin D with respiratory disease has been observed for more than 100 years, the potential benefits of vitamin D for the prevention of respiratory tract disease, including wheezing disorders, continue to be investigated in many observational and epidemiologic studies.1 However, a 2011 Institute of Medicine report concluded that the available evidence was insufficient to establish a functional relationship between vitamin D and any health outcome other than the maintenance of bone health across the lifespan, including prevention and treatment of infantile vitamin D deficiency rickets.2