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May 20, 1944


JAMA. 1944;125(3):196-200. doi:10.1001/jama.1944.02850210018004

One hundred years ago ridicule blasted the researches of Gruby, the founder of medical mycology. Fifty years later the discovery of bacteria overshadowed a brilliant revival by Sabouraud, who established a clinical differentiation of dermatophytes which still endures. New interest after World War I brought forth such a surge of literature on this subject that the old waste basket of dermatology, eczema, was replaced by the catch-all labeled fungous infections. Endemics of ringworm encouraged laboratory studies, and the finding of a threadlike strand or a small round body in a scraping or a filamentous growth on a culture medium was sufficient to assure the dermatologist that a cutaneous outbreak was a fungous disease. Molds and yeasts assumed a new role. Koch's laws were disregarded, and investigators attached their names to previously known fungi merely because change of medium, single spore transplant or environment had produced a change in color or

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