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In infants as in adults, neuromuscular disturbances of the bladder are a frequently observed cause of chronic pyuria and in some instances lead to an untimely death. Usually these disturbances are first manifested by abnormal vesical sphincteric activity which eventually results in functional and anatomic alterations in the bladder musculature, ureters and kidneys. Since the underlying etiology is neurogenic in character, relatively little can be done to effect a cure. The prognosis is uniformly grave. Infection supervenes early or late; often the kidneys are totally destroyed and these patients die in uremia with or without other complicating disease (e. g., pneumonia). Fortunately, the clinical manifestations are not always severe. Enuresis may be the end-result in mild cases, but paralytic incontinence may be present if the disease is advanced.
I am here presenting a study of twenty cases of neurogenic vesical dysfunction in infants and children. In eight of these the
CAMPBELL MF. NEUROGENIC VESICAL DYSFUNCTION IN INFANCY AND CHILDHOOD. JAMA. 1929;93(3):183–188. doi:10.1001/jama.1929.02710030019009
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