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Comment & Response
June 12, 2018

Reducing Calories to Lose Weight

Author Affiliations
  • 1Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
  • 2Biotechnology Center, University of Wisconsin-Madison, Madison
  • 3Department of Applied Health Science, Indiana University School of Public Health-Bloomington, Bloomington
JAMA. 2018;319(22):2336-2337. doi:10.1001/jama.2018.4257

To the Editor In a Viewpoint,1 Dr Guth said that the challenge of weight loss is to “convince patients to consume fewer calories” and benchmarked weight loss success against the 3500 kcal per pound rule. This view suggests that small decreases in diet calories will progressively result in substantial weight losses. However, the real relationship between diet calories and weight loss is more complicated.

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