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August 7, 2018

Type 2 Myocardial Infarction—Diagnosis, Prognosis, and Treatment

Author Affiliations
  • 1Department of Medicine, Massachusetts General Hospital, Boston
  • 2Brigham and Women’s Hospital Heart & Vascular Center, Harvard Medical School, Boston, Massachusetts
  • 3Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston
  • 4Cardiometabolic Trials Baim Institute for Clinical Research, Boston, Massachusetts
JAMA. 2018;320(5):433-434. doi:10.1001/jama.2018.7125

Over the past 3 decades, mortality rates for acute myocardial infarction (MI) have declined significantly in large part due to improved evidence-based revascularization techniques, medical therapies, and systems of care. Yet, patients with acute MI represent a diverse group with varying causes for their infarction. Recognizing this, in 2007, the Task Force for the Redefinition of MI created the Universal Definition of MI consensus document, which introduced 5 subtypes of MI (Table).1 One common subtype, type 2 MI, is defined as an MI driven by a myocardial oxygen supply and demand mismatch in the absence of coronary thrombosis.

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