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Article
July 27, 1929

THE INHERITANCE OF ANHIDROSIS ASSOCIATED WITH ANADONTIA

Author Affiliations

URBANA, ILL.

JAMA. 1929;93(4):277-279. doi:10.1001/jama.1929.02710040029010
Abstract

Several years ago, Thadani1 reported a toothless condition found among men of a certain community in India. These men, known as Bhudas, are further characterized by the occurrence of baldness. According to Thadani, the inheritance of these abnormalities is sex-linked.

Recently I discovered what is apparently an analogous case in which I have been able to trace the condition for six generations.

The pedigree of this family as shown in figure 1 was obtained from individuals IV-7 and V-11. Other information was obtained from the family physician and by examination of some of the members exhibiting the abnormal conditions.

The abnormal individuals are characterized by (1) an entire absence of teeth (anadontia) or in some cases the presence of only a few, which are abnormal in shape and are soft, whether deciduous or permanent teeth; (2) anhidrosis, or the inability to sweat, and (3) fine scanty hair on the

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