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July 24/31, 2018

Bundled Strategies for the Care of Children With Presumed Sepsis

Author Affiliations
  • 1Department of Pediatrics, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts
  • 2Pediatric Critical Care, Johns Hopkins All Children’s Hospital, St. Petersburg, Florida
JAMA. 2018;320(4):345-346. doi:10.1001/jama.2018.9183

Sepsis has been recognized by the United Nations World Health Assembly as a global threat to the health of children and adults. The World Health Organization has established as a priority the identification of strategies for prevention, early diagnosis, and treatment of sepsis.1

The increasing incidence of sepsis represents a major contributor to childhood morbidity. A cohort study involving US children’s hospitals demonstrated that the prevalence of sepsis among children (ages 18 years and younger) had increased from 3.7% in 2004 to 4.4% in 2012, and suggested that mortality and resource utilization have decreased over the same study period.2

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