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Clinical Trials Update
July 24/31, 2018

Exercise and Cognitive Decline in Dementia

JAMA. 2018;320(4):332. doi:10.1001/jama.2018.10153

Moderate- to high-intensity aerobic and strength exercise did not slow cognitive impairment in dementia, finds a trial published in BMJ.

The 494 participants with mild to moderate dementia (average age 77 years) were randomly assigned 2:1 to a supervised exercise and support program or to usual care. The intervention included 60- to 90-minute group sessions in a gym twice a week for 4 months, plus home exercises for 1 hour each week. After 4 months, participants were prescribed an unsupervised 150-minute per week home exercise program.