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Article
June 24, 1944

PATHOGENESIS OF MÉNIÈRE'S DISEASE

JAMA. 1944;125(8):556-557. doi:10.1001/jama.1944.02850260030014
Abstract

Ménière's disease is characterized by a combination of vestibular and auditory disorders. Vertigo is the chief and the disabling symptom, but deafness and tinnitus are so common that they must be regarded as part of the clinical picture. Ménière in 1861 suggested that these symptoms were due to a disorder of the inner ear and that the underlying lesion was an intralabyrinthine hemorrhage. Charcot, a contemporary of Ménière, observed that in some patients the attacks of vertigo ceased when deafness became complete. He suggested that the cure could be hastened by an intracranial section of the auditory nerve. The operation was not successfully performed until 1928, when Dandy1 reported a number of successful sections of the eighth nerve. "We know," he states, "that the acoustic division of the auditory nerve is affected because of the loss of hearing and that the vestibular branch is affected because of the diminished

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