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To the Editor:—
The subject of fluorine and its relation to dental caries is one which is receiving wide publicity in both the professional and the lay press. It has come to my attention that some dentists are advising their patients to use mouth washes containing sodium fluoride for self medication, and some of the solutions prescribed are as potent as 1 and 2 per cent solutions. Sodium fluoride is a highly toxic substance, and while its application in safe concentrations, under strict control by competent personnel, may prove to be a useful therapeutic agent, under other circumstances it may be definitely harmful.
Ast DB. POTENTIAL DANGER OF SELF MEDICATION WITH FLUORIDES. JAMA. 1944;125(12):867. doi:10.1001/jama.1944.02850300047024
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