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August 7, 2018

Incorrect Data

JAMA. 2018;320(5):510. doi:10.1001/jama.2018.9890

In the article entitled “Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases: A Randomized Clinical Trial” published in the July 26, 2016, issue of JAMA,1 duplicate patient data reported in eTable 4 in Supplement 2 led to incorrect data being reported in the Results sections of the abstract and the text. eTable 4 has been corrected. Data in the abstract on overall quality of life should have read “mean change from baseline, −1.3 vs −10.9 points; mean difference, 9.6; 95% CI, 3.6-15.6 points; P = .002.” Data on page 404 under the heading “QOL and Functional Independence” should have read “There were 71 and 53 patients in the SRS and SRS plus WBRT groups, respectively, for whom QOL data were available from baseline and from at least 1 subsequent evaluation. There was better QOL at 3 months with SRS alone, including overall QOL (mean change from baseline, −1.3 vs −10.9 points; mean difference, 9.6 points; 95% CI, 3.6-15.6 points; P = .002) and functional well-being (mean change from baseline, 0.4 vs −21.9 points; mean difference, 21.5 points; 95% CI, 4.6-38.4; P = .03).” This article was corrected online.

Brown  PD, Jaeckle  K, Ballman  KV,  et al.  Effect of radiosurgery alone vs radiosurgery with whole brain radiation therapy on cognitive function in patients with 1 to 3 brain metastases: a randomized clinical trial.  JAMA. 2016;316(4):401-409. doi:10.1001/jama.2016.9839PubMedGoogle ScholarCrossref