To the Editor The randomized clinical trial1 comparing opioid and nonopioid medications reflects real-world use and was conducted in a population with common reasons for chronic opioid use. The prospective nature of this study is important given the lack of correlation between patients’ actual benefit from chronic opioids and their perceptions of benefit.2
Covington E, Argoff C, Stanos SP. Opioids vs Nonopioids for Chronic Back, Hip, or Knee Pain. JAMA. 2018;320(5):507–508. doi:10.1001/jama.2018.6941
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