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Comment & Response
August 7, 2018

Opioids vs Nonopioids for Chronic Back, Hip, or Knee Pain

Author Affiliations
  • 1Cleveland Clinic Foundation, Shaker Heights, Ohio
  • 2Albany Medical Center, Albany, New York
  • 3Swedish Medical Center, Seattle, Washington
JAMA. 2018;320(5):507-508. doi:10.1001/jama.2018.6941

To the Editor The randomized clinical trial1 comparing opioid and nonopioid medications reflects real-world use and was conducted in a population with common reasons for chronic opioid use. The prospective nature of this study is important given the lack of correlation between patients’ actual benefit from chronic opioids and their perceptions of benefit.2