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Article
September 7, 1929

EFFECT OF HOMOLOGOUS TRANSPLANTS ON THE PROSTATE GLAND IN WHITE RATS

JAMA. 1929;93(10):759-760. doi:10.1001/jama.1929.02710100021008
Abstract

The results of numerous experimental transplantations of various tissues have been reported, but few investigations of this character have been attempted with the prostate gland.

Because of the apparent need for additional studies in this field, an investigation was made of the effect of partial and of complete prostatectomy on rats, and of the free transplantation of pieces of prostatic tissue into normal rats and into rats after complete prostatectomy.

Both young and fully mature rats were employed in these experiments. Three series of experiments were conducted. The sites chosen for transplantation were different, in order to eliminate any possible local influence. In the first series, the prostatic tissue was implanted subcutaneously in the abdominal wall, in the second series intraperitoneally and in the third series within the scrotum, the transplant being sutured to the tunica vaginalis. After varying periods of time, the transplants and also the prostate glands were

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