Robust validated prediction rules tested in randomized trials guide clinical decisions that reduce risk for major cardiovascular events, breast cancer, and numerous other conditions. With more than 2.4 million hospital discharges of patients with alcohol use disorder (AUD) per year in the United States,1 and after almost 70 years of research, clinicians might expect that the same prediction rules would exist to predict severe withdrawal. But these rules are not available.
Saitz R. Medications for Alcohol Use Disorder and Predicting Severe Withdrawal. JAMA. 2018;320(8):766–768. doi:10.1001/jama.2018.10061
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