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Here in compact form is a description of the cellular architecture of the human cortex, given in much greater detail in the monumental atlas with German text by Economo and Koskinas, published in 1925. The illustrations, mostly reproductions of photographs of all important cortical areas, add greatly to the value of the book. This line of investigation, together with the analogous study of the medullated fibers of the cortex —myelo-architectonics—has thrown important light on cortical functioning in health and in disease. In summarizing, Economo states, however, that apart from amyotrophic lateral sclerosis there is no general areal limitation of pathologic processes but that there is rather a regional selection of certain structural types of the cortex. There is, furthermore, a certain laminal affinity to disease, as a result of which the third layer is markedly affected in psychotic disturbances of the personality; while the diseases which primarily affect the capacity
The Cytoarchitectonics of the Human Cerebral Cortex. JAMA. 1929;93(10):794. doi:10.1001/jama.1929.02710100056050
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