The chemosurgical method was introduced by Mohs1 for the excision of accessible forms of cancer under microscopic control. The tissues in question are fixed in situ by means of a suitable solution of zinc chloride and then excised and examined microscopically. This process is repeated if necessary until microscopically cancer free surfaces are reached. The fixation of the tissue by the zinc chloride does not interfere with the microscopic work. A special clinic was established in the department of surgery in the University of Wisconsin eight years ago, and since then many hundreds of cases of cancer have been subjected to the chemosurgical treatment. The results are now becoming available for analysis and evaluation. The first report on these results deals with cancer of the lip.2
The report covers the cases treated between July 7, 1936 and May 29, 1943. The cure rates are 91.5 per cent of
CHEMOSURGICAL TREATMENT OF CANCER OF THE LIP. JAMA. 1944;126(1):32. doi:10.1001/jama.1944.02850360034012
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