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September 25, 2018

Treatment Algorithms for Staphylococcal Bacteremia: Improving Clinical Care and Enhancing Antimicrobial Stewardship

Author Affiliations
  • 1Division of General Internal Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City
  • 2Iowa City VA Health Care System, Iowa City, Iowa
  • 3Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor
  • 4Associate Editor, JAMA
JAMA. 2018;320(12):1243-1244. doi:10.1001/jama.2018.13315

Antimicrobial resistance is among the most important threats to human health.1 Lost in the episodic outbreaks of emerging pathogens such as 2009 H1N1 influenza, Ebola, and Zika virus has been the steady increase in resistance to commonly used antibiotics in frequently seen bacterial infections. Confronting antimicrobial resistance requires investment in 3 critical areas including (1) antimicrobial discovery, (2) rapid diagnostics, and (3) infection prevention and antimicrobial stewardship. In particular, algorithms based on clinical practice guidelines, that promote appropriate antibiotics and durations of therapy and limit unnecessary treatment, have the potential to enhance care for individual patients and improve public health more broadly.