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News From the Centers for Disease Control and Prevention
September 25, 2018

Opioid Use Disorder During Pregnancy

JAMA. 2018;320(12):1232. doi:10.1001/jama.2018.13546

National rates of opioid use disorders (OUD) among new mothers has quadrupled between 1999 and 2014, according to a CDC report.

The ongoing opioid epidemic has contributed to growing rates of prenatal opioid use, which can lead to preterm labor, stillbirth, neonatal abstinence syndrome (NAS), or maternal mortality. Based on an analysis of 1999-2014 hospital discharge data from the Healthcare Cost and Utilization Project (HCUP), the rate of maternal OUD increased from 1.5 to 6.5 per 1000 deliveries during that period. All 28 states with data available saw increases, but rates varied substantially from state to state, from a low of 0.7 per 1000 deliveries in the District of Columbia to 48.6 per 1000 deliveries in Vermont. The authors note the state-level differences in the prevalence of OUD during pregnancy may reflect differences in opioid prescribing and in rates of opioid use screening, diagnosis, and treatment of OUD and NAS.