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JAMA Insights
Clinical Update
October 9, 2018

Management of Chronic Wounds—2018

Author Affiliations
  • 1Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, California
JAMA. 2018;320(14):1481-1482. doi:10.1001/jama.2018.12426

Tissue repair following a wound occurs along a spectrum ranging from underhealing, as occurs in chronic wounds, to overhealing, as is seen in fibrosis.1 In the United States, it is estimated that as many as 4.5 million people have chronic wounds, resulting in substantial economic and psychosocial costs. Various pathologic states result in chronic wound development, including arterial or venous insufficiency, diabetes, undue skin pressure, presence of a foreign body, and infection.2

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