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News From the Food and Drug Administration
October 2, 2018

Tretinoin in New Lotion Formula

JAMA. 2018;320(13):1309. doi:10.1001/jama.2018.14129

The FDA has approved the first lotion formulation of the acne drug tretinoin to help ward off dryness, peeling, and sensitivity that often are associated with topical retinoids.

Marketed under the brand name Altreno, the lotion is indicated for patients aged 9 years or older who have acne vulgaris. Extensive clinical data show that topical retinoid therapy is highly effective in treating acne, but some patients avoid using it because it can irritate skin. The recently approved lotion formula, which contains moisturizing hyaluronic acid and collagen, was less irritating than a similar gel formulation.

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