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September 23, 1944


JAMA. 1944;126(4):237. doi:10.1001/jama.1944.02850390035014

During the last decade Forbes and his associates1 of the Institute of Animal Nutrition, Pennsylvania State College, have collected experimental evidence that with animals on equicaloric mixed diets progressive decrease in total heat production is associated with increases in protein percentage. This is contrary to general clinical belief, which assigns a dominant thermogenic role to protein. Forbes and Swift2 have emphasized the possible bearing of these results on current problems of military dietetics and animal husbandry.

Total heat production was measured in selected groups of white rats during seven hour experimental periods on two consecutive days, the animals sleeping during most of the period. The first determinations were made with the animals on a minimum basal diet. The experiment was repeated seven days later with the same rats on the same diet plus measured amounts of beef protein, dextrose or lard, tested alone or in combination. The increased

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