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November 6, 2018

Treatment of HypertensionAddressing a Global Health Problem

Author Affiliations
  • 1TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
JAMA. 2018;320(17):1751-1752. doi:10.1001/jama.2018.16579

Hypertension is the most common preventable cause of cardiovascular disease (CVD) worldwide. It is commonly referred as a “silent killer” because it gradually damages the heart, blood vessels, and other organs without any apparent symptoms. Elevated blood pressure (BP) is a major risk factor for myocardial infarction, heart failure (HF), stroke, chronic kidney disease, peripheral artery disease, and atrial fibrillation. Although hypertension can be readily diagnosed, and in most instances successfully treated with improvements in lifestyle and with well-tolerated inexpensive medications, hypertension continues to be a major cause of global morbidity and mortality.

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