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Comment & Response
November 20, 2018

Odds Ratios vs Risk Ratios

Author Affiliations
  • 1University of North Carolina at Chapel Hill
JAMA. 2018;320(19):2041. doi:10.1001/jama.2018.14417

To the Editor Dr Norton and colleagues1 described significant limitations of odds ratios (ORs) but they did not report one important advantage of ORs compared with risk ratios (RRs): the magnitude of the association between an exposure and a dichotomous outcome is invariant to whether the outcome is defined as event occurrence (eg, death) or nonoccurrence (eg, no death; ie, survival).2