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Clinical Trials Update
November 27, 2018

Behavior Therapy for Cognitive Decline

JAMA. 2018;320(20):2068. doi:10.1001/jama.2018.18510

Therapy designed to increase cognitive, physical, and social activity prevented cognitive decline in black individuals with mild cognitive impairment, found a study in JAMA Neurology. Black people are underrepresented in clinical trials and have twice the incidence of dementia as white people.

In the study, 221 black individuals with mild cognitive impairment were randomly assigned to behavior activation or to a control group (supportive therapy). Behavior activation therapy provides support to help individuals meet their cognitive, physical, and social goals associated with preventing cognitive decline. In supportive therapy, participants discussed feelings related to aging and memory loss with a therapist who offered encouragement. Each group participated in 11 in-home, 60-minute sessions over 2 years.

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