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Clinical Trials Update
November 27, 2018

Hypertension Drug Fails to Slow Cognitive Decline

JAMA. 2018;320(20):2068. doi:10.1001/jama.2018.18513

The hypertension medication nilvadipine, a dihydropyridine calcium channel blocker, did not slow cognitive decline in patients with mild to moderate Alzheimer disease (AD), found a study published in PLOS Medicine. In a previous small study of patients with hypertension and mild cognitive impairment, nilvadipine stabilized cognitive decline.