A 68-year-old woman with Rai stage 0 chronic lymphocytic leukemia (CLL) presented with a 2-day history of dyspnea on exertion. She reported no cough, chest pain, orthopnea, leg swelling, or viral-like symptoms. Her temperature was 36.8°C, heart rate 102/min, respiratory rate 22/min, and blood pressure 124/76 mm Hg. She had conjunctival pallor and scleral icterus, but no lymphadenopathy, hepatosplenomegaly, or ecchymosis. Results of initial laboratory testing are presented in the Table.
Eule C, Gupta A, Nagalla S. The Direct Antiglobulin Test for Evaluating Anemia. JAMA. 2018;320(24):2593–2594. doi:https://doi.org/10.1001/jama.2018.14317
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