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Biotech Innovations
December 11, 2018

Artificial Intelligence Tools for Sepsis and Cancer

JAMA. 2018;320(22):2303. doi:10.1001/jama.2018.19383

Researchers at Imperial College London are developing an artificial intelligence (AI) agent to help physicians select optimal fluid and vasopressor doses for adult patients with sepsis in intensive care units (ICUs).

The clinical decision support tool, dubbed the AI Clinician, was developed on a data set from 5 ICUs and more than 17 000 sepsis admissions in a single US tertiary teaching hospital and recently described in Nature Medicine. It used reinforcement learning to identify personalized treatment strategies based on patient characteristics, such as demographics, vital signs, and laboratory tests, as well as administered fluid and vasopressor doses and associated patient outcomes.