Every case of orbital tumor presents a problem in diagnosis. Features concerning the onset and course of signs and symptoms of tumor are the factors which, when put together, constitute the basis for distinction from diseases of the orbit that simulate tumor. These factors are open to various interpretations, for the significance of any one of them must be regarded in the light of all other factors that can be ascertained. Certain signs are present in some degree in progressive stages of growth of all orbital tumors. For the most part they are anatomic and result from changes of situation and size of the tumor with displacement of the globe and orbital contents. As all orbital tumors are space-taking lesions, the displacement of the eyeball, usually proptosis, is the most common of the early signs and is easily discernible in most cases by inspection alone without use of instruments. Changes
BENEDICT WL. DIAGNOSIS OF ORBITAL TUMORSADDRESS OF THE GUEST OF HONOR. JAMA. 1944;126(14):880–884. doi:10.1001/jama.1944.02850490014005
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