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Comment & Response
December 18, 2018

Cardiovascular Health and Cognitive Decline

Author Affiliations
  • 1Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
JAMA. 2018;320(23):2483. doi:10.1001/jama.2018.17554

To the Editor In their population-based cohort study, Dr Samieri and colleagues1 found that positive measures of cardiovascular health were associated with a lower risk of dementia and lower rates of cognitive decline. An important limitation of the data analysis, however, is that the investigators did not address the potential influence of depression or antidepressant treatment on their cognitive outcomes of interest.