To the Editor In their population-based cohort study, Dr Samieri and colleagues1 found that positive measures of cardiovascular health were associated with a lower risk of dementia and lower rates of cognitive decline. An important limitation of the data analysis, however, is that the investigators did not address the potential influence of depression or antidepressant treatment on their cognitive outcomes of interest.
Howland RH. Cardiovascular Health and Cognitive Decline. JAMA. 2018;320(23):2483. doi:10.1001/jama.2018.17554
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