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Research Letter
Evidence Report
January 29, 2019

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Author Affiliations
  • 1Kaiser Permanente Research Affiliates Evidence-based Practice Center, Kaiser Permanente Center for Health Research, Portland, Oregon
JAMA. 2019;321(4):404-406. doi:10.1001/jama.2018.17847

Gonococcal ophthalmia neonatorum (GON) is a neonatal conjunctival infection transmitted intrapartum from mothers infected with Neisseria gonorrhoeae to their newborns. Although GON is rare in the United States, with 0.4 cases or fewer per 100 000 live births per year during 2013-2017,1 prevention remains important because of high risk of corneal perforation and blindness, which can develop within 24 hours after delivery.2