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January 6, 1945

TREATMENT OF GONOCOCCIC VULVOVAGINITIS: A STUDY OF 442 CHILDREN

JAMA. 1945;127(1):6-9. doi:10.1001/jama.1945.02860010008002
Abstract

Gonococcic vulvovaginitis is a disease affecting the portio of the cervix, the vagina and the vulva of female infants and children. Its manifestations are a purulent discharge, edema, redness and tenderness of the parts affected, and occasionally lower abdominal pain. Complications of the disease are relatively rare.1 The disease is spread only by contact with infected purulent vaginal discharge; hence its spread does not become epidemic. Furthermore, if the child is not treated she usually ceases to have a profuse discharge after six to eight weeks and frequently is cured spontaneously a few weeks after this time.2 Therefore it is obvious that gonococcic vulvovaginitis is a very mild disease. Its treatment should aim at clearing up the purulent discharge as quickly as possible with an agent that is relatively innocuous to the patient. A recent careful study of this problem in New York City2 among a group

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