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January 13, 1945


JAMA. 1945;127(2):88-89. doi:10.1001/jama.1945.92860020002009a

Over the years a great number of preparations have been recommended and widely used in the treatment of scabies, not one of which has proved entirely satisfactory. Until comparatively recently preparations containing sulfur have probably been more universally used than others. Owing to the lengthy treatment necessary and the high percentage of untoward skin reactions, sulfur preparations are being rapidly replaced by benzyl benzoate.

A review of the literature discloses that more uniformly satisfactory results have been credited to the use of benzyl benzoate preparations than to any other sarcopticide heretofore used. It is reported that Nielson1 of Copenhagen began using 25 per cent benzyl benzoate in the treatment of scabies in 1912. However, not until its reintroduction by Kissmeyer2 did it receive much public acclaim. Soon after his original paper, benzyl benzoate became widely used in Great Britain,3 but not until quite recently has it received due