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January 13, 1945


JAMA. 1945;127(2):120. doi:10.1001/jama.1945.02860020064022

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To the Editor:—  In an editorial comment in The Journal, Dec. 2, 1944 you call attention to a highly interesting observation on the Giles identical twins, namely the remarkable resemblance to each other in the successive steps of their intellectual development and accomplishment. To a geneticist this information is certainly of interest. I wish to add to the striking resemblance in all such cases of normal life instances in pathologic life of identical twins.In a contribution presented at the May 1925 meeting of the Philadelphia Psychiatric Society (Am. Med.20:603 [Oct.] 1925) I submitted in great detail records of two pairs of twins. Briefly, one group consisted of two brothers who showed equal intellectual ability. At the age of 19 one commenced to show signs of psychotic disorder, namely negligence at work, paroxysms of violent anger, sleeplessness, then carelessness with regard to his clothes, gradual loss of interest

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