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Comment & Response
February 19, 2019

Long-term Follow-up of Antibiotics vs Surgery for Appendicitis

Author Affiliations
  • 1The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
JAMA. 2019;321(7):706. doi:10.1001/jama.2018.19591

To the Editor The study by Dr Salminen and colleagues1 compared antibiotic therapy alone vs appendectomy to treat uncomplicated acute appendicitis. The cumulative incidence of appendicitis recurrence after 5 years was 39.1% in the antibiotic group. The complication rate was 6.5% in the antibiotic group and 24.4% in the surgical group. We have several concerns about these results.