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Clinical Trials Update
February 26, 2019

BMI Not a Good Proxy for Breast Cancer Risk

JAMA. 2019;321(8):735. doi:10.1001/jama.2019.0886

Postmenopausal women with normal body weight may be at increased risk of breast cancer if they have high amounts of body fat, reported a study in JAMA Oncology.

The secondary analysis of a cohort enrolled in the Women’s Health Initiative clinical trial and observational study included 3460 postmenopausal women with normal body mass index (BMI) who had dual-energy x-ray absorptiometry (DXA), a highly accurate measure of adiposity, at baseline and 1, 3, 6, and 9 years follow-up.