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January 27, 1945


JAMA. 1945;127(4):219. doi:10.1001/jama.1945.92860040003007a

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Mrs. L. H., aged 26, a waitress, married eight years, with 1 son aged 7 years, first called at the office June 7, 1944 with a severe dermatitis of four years' duration.

She had been in good health until shortly after she changed her place of employment. She had a maculopapular eruption (areas of serous exudate covered with crustations and areas of parchment-like induration with a severe inflammatory base). The lesions began from the tips of the fingers of both hands, extending over the dorsum of the hand and the anterior and posterior surfaces of the forearm and arm, more pronounced on the flexor surfaces of both forearms, where the induration and erythema were extreme. In the last year it had also spread to the back of the neck. The rash was accompanied by severe pruritus, especially at night, and for weeks at a time the patient obtained little sleep.

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