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Comment & Response
March 5, 2019

Weight Loss Interventions in Adults

Author Affiliations
  • 1Department of Metabolic-Surgical Weight Management, Kaiser Permanente, Denver, Colorado
  • 2Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, Massachusetts
  • 3Weight Center, Massachusetts General Hospital, Boston
JAMA. 2019;321(9):900. doi:10.1001/jama.2018.20287

To the Editor The US Preventive Services Task Force (USPSTF)1 recommended high-intensity counseling for adults with obesity, followed by regular contact for maintenance of weight loss. The task force did not issue recommendations for pharmacotherapy because of (1) perceived lack of generalizability of the clinical trial findings, owing to stringent inclusion criteria and run-in periods; (2) high rates of dropout in the trials; and (3) lack of data “about the maintenance of improvement after discontinuation of pharmacotherapy.”