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February 3, 1945

TREATMENT OF VINCENT'S ANGINA WITH SULFATHIAZOLE

JAMA. 1945;127(5):277. doi:10.1001/jama.1945.92860050001007
Abstract

That Vincent's organisms are frequently found in smears taken from a normal mouth is now common knowledge. They have been found in about 75 per cent of adult mouths examined, in spite of the absence of symptoms of Vincent's angina or Vincent's gingivitis, by Stafne. Their presence in smears taken for microscopic study should not be a basis for a diagnosis of Vincent's angina in the absence of clinical symptoms and signs, but when a patient is seen who has a sore throat, elevated temperature, a membrane on the throat or tonsil with a necrotic tonsillar ulcer and a smear showing numerous fusiform bacilli, and Borrelia, it can definitely be stated that the Vincent's organisms are the cause of the condition.

Arsenicals, as well as bismuth, have been shown by Ludwick,1 Farrell and McNichols,2 Jewesbury,3 Farley4 and others

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