To the Editor Drs Sisti and Joffe1 described challenges in conducting research on suicide. We agree that such research should include individuals with suicidal behavior and that suicide attempts and death are appropriate outcomes for trials. We also agree that conceptualizing the outcome of suicide as an adverse event might trigger objections by regulatory bodies that jeopardize the feasibility of such investigations.
Coffey CE, Ahmedani BK, Coffey MJ. Challenges in Research on Suicide Prevention. JAMA. 2019;321(11):1105. doi:10.1001/jama.2018.21951
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